Reading room in a University of Chicago library
RISK AREAS

Four fronts of catastrophic risk.

Necessarily interdisciplinary, cutting across technology, policy, and international security.

01 — PRIMARY RISK AREAS

Artificial Intelligence

AI capabilities are developing at an exponential rate. AI experts are warning of potentially catastrophic consequences of the technology they themselves are developing, including misinformation campaigns, reduced barriers to bioterrorism, and rogue autonomous models.

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Nuclear

Thousands of nuclear weapons around the world remain on hair-trigger alert — a false alarm or a single impulsive decision away from conflagration. Once launched, a missile cannot be recalled or shot down.

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02 — SECONDARY RISK AREAS

Biosecurity

Rising ability to engineer pathogens, and a history of laboratory leaks, threaten outbreaks of unprecedented danger. XLab's biosecurity research program is in early development.

Climate

Feedback effects beyond a tipping point could lead to catastrophic outcomes. XLab's climate risk research program is in early development.

More on These Risks

SCREENING

A House of Dynamite

With the Bulletin of the Atomic Scientists, XLab hosted a screening of Kathryn Bigelow's nuclear-war thriller.

PANEL

The Doomsday Clock

A panel discussion on the Bulletin of the Atomic Scientists' annual Doomsday Clock announcement.

RESEARCH

Rethinking Priorities for Frontier AI Security

A 2025 fellow's paper on prioritization in frontier AI security research.

Work on these problems with us.

Our Summer Research Fellowship trains the next generation of researchers across these risk areas.

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